Did you know that genes can mask and alter the effects of other genes? Could this process, called epistasis, be a key to understanding complex conditions like Alzheimer’s disease and diabetes?

A team of researchers from Skoltech and their Russian and U.S. colleagues have gathered two dozen mushrooms of the species Schizophyllum commune and analyzed their DNA, gaining insights into mutations ...

Deep mutational scanning of the CR9114 antibody reveals that epistasis and pleiotropy make cross-reactive breadth against ...

Jim Manzi has a long post up on epistasis, that is, gene-gene interactions: We could call this process of competing algorithms struggling to find the best solution as fast as possible "meta-evolution" ...

Euan Ashley's lab explores the intricate interactions of gene variants. Tiny "typos," or genetic mutations, can sneak into segments of DNA. Many of these are harmless, but some can cause health ...

Imagine your doctor calls you to discuss the results of your genetic testing. They tell you your results indicate you are highly likely to develop Alzheimer's disease. But not to worry, because they ...

Why evolutionary genetics does not always add up / Edmund D. Brodie III -- Beyond the average : the evolutionary importance of gene interactions and variability of epistatic effects / Patrick C.

For over a century, biologists have had to contend with a complicated picture of genetics, which they’ve only recently begun to understand. Does an unseen force lurk within genetics? Biologists have ...

Each week, we answer frequently asked questions about life during the coronavirus crisis. If you have a question you'd like us to consider for a future post, email us at goatsandsoda@npr.org with the ...