WashU Medicine researchers have verified the accuracy of genetics tools to correctly identify all the rare DNA changes that ...

When we think about genetic inheritance, we usually leap to DNA, the four-letter code containing the instructions for building a living organism. Scientists know that DNA encodes everything from hair ...

Gallstone disease is common, but its genetic basis remains incompletely understood. Here, the authors conduct a trans‑ancestry GWAS identifying 116 risk loci, linking gallstone susceptibility to lipid ...

A newly introduced open-access educational web platform links traditional capillary electrophoresis profiles with ...

Forty years ago, a postdoctoral researcher named James McGrath who would go on to spend more than three decades as a clinical geneticist and research scientist at Yale, made a discovery that advanced ...

University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited. Dr. Anne Hahn and Associate Professor Steven Zuryn from UQ's ...

A new review maps how prime editing, a CRISPR-derived tool capable in principle of correcting 89 percent of human pathogenic ...

Scientists have long known that the DNA code in genes is not the only way to pass genetic traits from parents to offspring. "Epigenetic" marks—chemical modifications to DNA that don't change the DNA ...

Modern humans carry DNA from two mysterious extinct lineages in addition to Neanderthals and Denisovans. Their hidden genetic legacy shows that our evolutionary past was shaped by repeated mixing ...

Researchers at Kanazawa University and the National Institute of Genetics in Japan have used high-speed atomic force ...

Most people with ALS don’t have a family history of it. Still, some cases of ALS are linked to inheriting specific gene mutations. Even nonfamilial cases can be linked to sporadic gene mutations that ...