In 2020, Jennifer Doudna won the Nobel Prize in chemistry for her work on the CRISPR-Cas9 gene-editing technology that allows ...

Cancer has often been explained through mutations in deoxyribonucleic acid (DNA) or changes in ribonucleic acid (RNA), but ...

When we think about cancer risk, it’s natural to wonder, “is it genetic?” The truth is, sometimes it is, but in many cases, cancer develops from a mix of lifestyle, environmental factors, and DNA ...

Cancer cells often survive treatment by fixing the DNA damage that therapy is meant to cause. Researchers found that UNI418 ...

Mitochondria act as energy factories in cells and have their own, separate DNA. Mutations to mitochondrial DNA (mtDNA) have been observed in cancer, but it has been unclear how these changes might ...

DNA-based methods dominate molecular cancer diagnostics but struggle to detect gene fusions and assess splice site consequences. RNA sequencing enables sensitive fusion detection and direct assessment ...

A CRISPR system detects rare cancer mutations in blood with single-nucleotide precision, outperforming ddPCR through engineered RNA guides and isothermal amplification. (Nanowerk Spotlight) Hidden ...

IN THE POPULAR imagination, cancer starts with a mutation in the DNA of a normal cell. That mutation allows the cell to multiply uncontrollably, circumventing the body’s usual quality-control checks.

DNA sits in sunlight every day, absorbing ultraviolet radiation that can set off the kind of chemical changes linked to ...