A 2026 review summarizes advances in CRISPR-Cas9 precision, delivery and primary-cell engineering for genetic diseases and ...

In this interview, Prof. Samuel Sternberg discusses how studies of CRISPR-Cas systems led to the discovery of RNA-guided DNA ...

Drug-resistant tuberculosis remains one of the most stubborn obstacles in global infectious disease control, and a new mini ...

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions—but there is always room for improvement. A new paper by investigators from Mass General Brigham ...

Thanks to CRISPR, medical specialists will soon have unprecedented control over how they treat and prevent some of the most challenging genetic disorders and diseases. CRISPR (Clustered Regularly ...

In a new study published in Nature titled, “Custom CRISPR-Cas9 PAM variants via scalable engineering and machine learning,” researchers from Massachusetts General Hospital (MGH) and Harvard Medical ...

Structural alterations of the genome are commonly observed in human cancer and can contribute to tumorigenesis through a variety of mechanisms including the formation of fusion oncoprotein and changes ...

Chinese Hamster Ovary (CHO) cells have been the industrial workhorse for production of biopharmaceuticals since the 1980s, with the first CHO-derived product approved by the FDA in 1987. Nearly five ...

In 2012, a powerful new gene editing tool took the scientific world by storm. Developed by a research team that included a recipient of the U.S. National Science Foundation's prestigious Alan T.