Our Astros vs. Mariners predictions tell Seattle to put away the brooms with my MLB picks hopping on Houston. The Houston Astros took a 6-1 beating on Sunday but were without SS Jeremy Pena and 3B Carlos Correa.

Houston has been hit hard by injuries in the early going of the 2026 season

Mariners right-handed pitcher Bryce Miller has spent the entire MLB season on the injured list.

Seattle handled business the way contenders should, finishing off a four-game sweep of the battered Astros before a much tougher series in San Diego.

Josh Naylor clubbed his first two home runs of the season as he drove in five runs, and the Seattle Mariners completed a four-game sweep of the Houston Astros with a 6-2 win on Monday afternoon.

Ahead of the game, Astros manager Joe Espada spoke with reporters and explained the decision. Espada said Correa has not fully recovered from his recent illness and would receive the day off, indicating he likely will not be available off the bench, according to Matt Kawahara of the Houston Chronicle.

These are the three biggest positives to a disappointing season's start.