The carving up of the amyloid precursor protein (APP) by the successive action of β- and γ-secretases liberates Aβ, but also yields a small intracellular fragment, the APP intracellular domain (AICD).

Activation-induced cell death (AICD) of immune cells is widely believed to be crucial for the regulation of immune responses. Although macrophage apoptosis has been observed under a variety of ...

When the amyloid precursor protein (APP) gets chopped up to make Aβ, other fragments are released, including APP’s intracellular domain. Scientists believe AICD acts as a transcription factor, though ...

If you haven’t had to perform CPR for a patient who was being shocked by an automated implant­able cardioverter defibrillator (AICD), give it time. Approximately 800,000 people in the United States ...