Nicotinic acetylcholine receptors (nAChRs) are pentameric ligand‐gated ion channels widely expressed in the central and peripheral nervous systems. Subtypes such as homomeric α7 and heteromeric α4β2 ...

Alzheimer’s disease (AD) is characterised by progressive cognitive decline, synaptic loss and neuroinflammation. Central to these processes is the cholinergic system, in which nicotinic acetylcholine ...

In healthy people, binding of the molecule acetylcholine (ACh) to its receptor (AChR) on skeletal muscle cells triggers muscle contraction underlying regular daily activities. In the autoimmune ...

India, May 31 -- Why do some people become addicted to nicotine after relatively little exposure, while others are able to ...