The sudden death last week of award-winning actress Catherine O'Hara drew attention to her rare condition, dextrocardia with situs inversus, which she only learned about in adulthood. "My heart is on the right side, and all my organs are flipped," O'Hara shared in a 2021 interview.

Two years ago, Oscar night. Backstage. Catherine O’Hara and I have mere minutes before we walk out to present, and we’re riffing on how to make a funny entrance. She says, “How ‘bout when they introduce us, you go out real fast without waiting for me, and I’ll go—’Hey, wait!’” “Yeah. I like it. Let’s do that,” I say.

PEOPLE's new cover story looks at the legacy of the 'Home Alone' and 'Beetlejuice' actress, who died at 71 on Friday, Jan. 30

Catherine O'Hara has died at 71. The Emmy-winning actor was known for her roles on “SCTV,” “Schitt's Creek,” and the two “Home Alone” films.

Tributes for Catherine O’Hara have been pouring in after the news of her sudden death. The actor died on Jan. 30 at the age of 71, her manager confirmed to NBC News. O’Hara died at home after a brief illness,

The Canadian actress’s oddball utterances became lasting comedic earworms, among them her one-word scream in “Home Alone”: “Kevin!”

Celebrities and Canada's prime minister are reacting to the death of actor Catherine O'Hara, who died Friday in Los Angeles at 71.

Eugene Levy paid his respects to his decades-long friendship with Catherine O'Hara saying "Words seem inadequate to express the loss I feel today."

"I was standing in swanky restaurant in New York City wearing a black dress short enough to satisfy management, and I had just broken the most important rule of the job."

The late, great Catherine O'Hara starred in many great family and kids movies, including Home Alone, Beetlejuice, and The Nightmare Before Christmas.